Care Recommendations

The recommendations in TIRO are based on the published recommendations for thyroid nodule and for thyroid cancer management. They are not intended to be “new guidelines.” Instead, TIRO is an amalgamation of published recommendations born out of the rigorous process of developing guidelines by a variety of international organizations. By highlighting the commonalities and the discrepancies, we aim to direct the clinician as to the optimal standards of care that currently exist.

Differentiated Thyroid Cancer

• Use of Radioactive Iodine
• Systemic Therapy
• Initial Staging & Response to Therapy
• Recurrent & Persistent Disease
• Initial Management
• Initial Evaluation of Thyroid Nodules

Medullary Thyroid Cancer

• Initial Evaluation of Thyroid Nodules Suspicious of MTC
• Management of Inherited Forms
• Surgical Management

Anaplastic Thyroid Cancer

• Diagnostic Procedures
• Initial Staging & Treatment Planning
• Surgical Management
• Systemic Therapy
• End of Life Care

Who Developed TIRO?

Created by a Multidisciplinary & International Advisory Board

Endocrinology

Michael Tuttle, MD

Executive Member

Memorial Sloan Kettering Cancer Center

Camilo Gonzalez-Velazquez, MD

Executive Member

Universidad Autonoma de Nuevo León

Erik Alexander, MD

Executive Member

Brigham and Women’s Hospital

Andrew Bauer, MD

University of Pennsylvania

Juan Pablo Brito, MD

International Leadership Council

Mayo Clinic

Naifa Busaidy, MD

MD Anderson

Fabian Pitoia, MD, PhD

Universidad de Buenos Aires

Mara Y. Roth, MD

University of Washington

Eyal Robenshtok, MD

International Leadership Council

Rabin Medical Center

Nuclear Medicine

Monica Rossleigh, MD

Executive Member

Prince of Wales Hospital

David Pattison, MD

Royal Brisbane Hospital

Radiation Oncology

Jill Langer, MD

Penn Medicine

Kate Newbold, MD

The Royal Marsden

Cytopathology
& Histopathology

Zubair Baloch, MD, PhD

Penn Medicine

Jeffrey Krane, MD, PhD

UCLA Health

Endocrine Surgery

Janice Pasieka, MD, FRCSC, FACS

Executive Member

University of Calgary

Carrie Cunningham, MD

Massachusetts General Hospital

Iwao Sugitani, MD, PhD

International Leadership Council

Nippon Medical School, Graduate School of Medicine

Head & Neck Surgery

Mark Urken, MD, FACS, FACE

Executive Member

Mount Sinai

Dana Hartl, MD

International Leadership Council

Gustave Roussy

Lisa Orloff, MD

Stanford

Mark Zafereo, MD

MD Anderson

Medical Oncology

Lori Wirth, MD

Executive Member

Massachusetts General Hospital

Frank Worden, MD

University of Michigan