TOP

What is TIRO?

TIRO helps medical professionals optimize the care of their patients by guiding them through the existing evidence.

TIRO Thyroid International Recommendations Online monogram logo

TIRO (Thyroid International Recommendations Online) is a compilation of multiple, widely-recognized international thyroid nodule and thyroid cancer guidelines from the United States, Europe and Japan. TIRO puts all of the most up-to-date guidelines in one easy to access site.

In addition, it compares and contrasts international thyroid cancer and thyroid nodule guidelines, white papers and recommendations in a way that identifies where guidelines align and where discrepancies exist. It acts as a dynamic resource for clinicians on contemporary topics via weekly journal clubs, lectures, tumor boards and round table discussions. This program is led by a multidisciplinary board composed of top thyroid specialists from around the world.

Why We Created TIRO

TIRO was developed in an effort to place guideline-based recommendations at the fingertips of clinicians who are managing patients with both thyroid nodules and thyroid cancer. In many respects, by collating information from multiple sources, TIRO is the thyroid guideline of all guidelines.

The current published guidelines are static and both difficult to access and challenging to navigate. TIRO is designed to address these issues and to facilitate the delivery of optimal patient care at the point of care. In addition, the current guidelines are often outdated soon after they are published. In many instances, the published recommendations are based on less than optimal evidence, as well as expert opinion where quality evidence does not exist.

TIRO aims to offset these traditional handicaps. The goal of TIRO is to provide relevant, updated information in specific areas where the evidence is weak and where discrepancies exist across guidelines that have been reviewed. This process is based on the tremendous amount of new studies that are published in the literature on a regular basis and which are highlighted in our weekly virtual educational sessions that are delivered and recorded and then strategically placed in the relevant locations within the recommendation sections of TIRO. In this way, we intend to provide a dynamic and continually updated resource.

The Creators of TIRO Practice All Over the World

  • Alberta, Canada
  • Monterrey, Mexico
  • Boston, MA
  • New York, NY
  • Los Angeles, CA
  • San Francisco, CA
  • Ann Arbor, MI
  • Rochester, MN
  • Philadelphia, PA
  • Houston, TX
  • Seattle, WA
  • Buenos Aires, Argentina
  • Brisbane, Australia
  • Melbourne, Australia
  • Sydney, Australia
  • Mainland China
  • Tokyo, Japan
  • Paris, France
  • Tel Aviv, Israel
  • London, UK

Upcoming Webinars

Michael Tuttle, MD

Moderator

Tumor Board

Cases presented by Dr. Jorgelina Guerra

Dec. 12, 2025

Dr. Kate Newbold

Guest Presenter

Journal Club

Use of Lenvatinib in the Treatment of Radioiodine-refractory Differentiated Thyroid Cancer: A Multidisciplinary Perspective for Daily Practice

Dec. 19, 2025

No Webinar

Happy Holidays!

Dec. 26, 2025

No Webinar

Happy New Year!

Jan. 2, 2026

William Speier, MD

Guest Presenter

Journal Club

Combining Ultrasound Imaging & Molecular Testing in a Multimodal Deep Learning Model for Risk Stratification of Indeterminate Thyroid Nodules

Jan. 9, 2026

Michael Tuttle, MD

Moderator

Tumor Board

Cases presented by Dr. Joyce Shin

Jan. 16, 2026